看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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Currently available feasibility data for possible combination strategies. , M% ]( s6 O% J
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3 p+ ]0 g2 N0 V, C M6 N* lCombination Feasibility according to preliminary data
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( k1 G$ o2 S; s- k& v VBevacizumab + sorafenib Yes, reduced dose
* w6 p3 {3 L- d' K5 mBevacizumab + sunitinib† No 4 U$ D7 b( Q \8 n
Bevacizumab + temsirolimus Yes
" ]3 J& H" Q9 s, ?" {, l! ]0 }6 PBevacizumab + everolimus Yes
0 j$ `/ v! w; s+ ^4 \" c5 }Sorafenib + sunitinib ?
& r" W: e5 V( vSorafenib + temsirolimus Yes, reduced dose
# m2 I% H2 N9 \Sorafenib + everolimus Yes, reduced dose 6 `* R& |+ G; h
Sunitinib + temsirolimus† No # L/ @- z* Z6 T5 {
Sunitinib + everolimus ?
/ z+ X- C+ P8 aTemsirolimus + everolimus ? + C' p; {1 K# F0 H% B1 F& A7 D
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†Led to US FDA warning.; U6 d- p. P" h( v0 @& o7 t9 x
?: As yet unattempted combination.* q. P5 G! ]+ R1 m
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